Having the highest or most prominent part among a group of similar voices or instruments. B1 [ s ] the first person or thing to do or be something, or the first person or thing mentioned: First interstate is a community bank offering a variety of services including home loans, commercial loans, wealth management, online/mobile banking, and more. (”fhis”), a subsidiary of first horizon bank. Initial, inaugural, earliest, foremost, original, maiden, previous, early;